CD8a / Fluorescein / 53-6.7
CD8a / Fluorescein / 53-6.7
Product Details
| Supplier | R&D Systems | |
|---|---|---|
| Catalog #: | FAB116F-100 (View supplier product page) | |
| Size | 100 Tests | |
| Price | $129.00 | |
| Antigen | CD8a | |
| Clone | 53-6.7 | |
| Host | Rat | |
| Isotype | IgG2a | |
| Conjugate | Fluorescein | |
| Target Species | Mouse | |
| Applications | FC | |
| Description | Mouse CD8 alpha Fluorescein-conjugated Antibody |
About CD8a and Fluorescein
| CD8a | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020] | |
|---|---|---|
| Fluorescein | Fluorescein is an organic fluorophore first synthesized by Aldolf Bayer in 1871. FITC, an amine-reactive derivative, is also a commonly used name for this dye. It has an excitation peak at 494 nm and an emission peak at 512 nm. |
Images
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Detection of CD8 alpha in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse CD3 APC-conjugated Monoclonal Antibody (Catalog # FAB4841A) and either (A) Rat Anti-Mouse CD8 alpha Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB116F) or (B) Rat IgG2A Fluorescein Isotype Control (Catalog # IC006F). View our protocol for Staining Membrane-associated Proteins. |
Citations
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Reviews & Ratings
Fluorescein Excitation and Emission Spectra
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