MMP-3 / Alexa Fluor 405 / 50647

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB513V (View supplier product page)
Size 500 μl
Price $759.00
Antigen MMP-3
Clone 50647
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 405
Target Species Human
Applications WB, IHC, ICS, CyTOF
Description MMP-3 Antibody (50647) [Alexa Fluor® 405]
About MMP-3 and Alexa Fluor 405
MMP-3 Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 405 Excitation and Emission Spectra