MGMT / Alexa Fluor 405 / MGMT/8128R

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-21105AF405 (View supplier product page)
Size 100 μl
Price $629.00
Antigen MGMT
Clone MGMT/8128R
Host Rabbit
Isotype IgG κ
Conjugate Alexa Fluor 405
Target Species Human
Applications IHC-P
Description MGMT Antibody (MGMT/8128R) [Alexa Fluor® 405]
About MGMT and Alexa Fluor 405
MGMT Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. [provided by RefSeq, Sep 2015]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 405 Excitation and Emission Spectra