MGMT / DyLight 488 / MGMT/8364R

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-21104G (View supplier product page)
Size 100 μl
Price $629.00
Antigen MGMT
Clone MGMT/8364R
Host Rabbit
Isotype IgG κ
Conjugate DyLight 488
Target Species Human
Applications IHC-P
Description MGMT Antibody (MGMT/8364R) [DyLight 488]
About MGMT and DyLight 488
MGMT Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. [provided by RefSeq, Sep 2015]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra