BA 46 GLQHWVPEL (Dextramer) / FITC / MFG-06

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-11473F (View supplier product page)
Size 100 μl
Price $629.00
Antigen BA 46 GLQHWVPEL (Dextramer)
Clone MFG-06
Host Mouse
Isotype IgG1 κ
Conjugate FITC
Target Species Human
Applications IHC, IHC-P
Description MFG-E8 Antibody (MFG-06) [FITC]
About BA 46 GLQHWVPEL (Dextramer) and FITC
BA 46 GLQHWVPEL (Dextramer) This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
FITC Fluorescein isothiocyanate (FITC) has an excitation peak at 495 nm and an emission peak at 519 nm. The name FITC is a misnomer in that the isothiocyanate is a reactive form of this dye. Once FITC is conjugated to an antibody, it is simply Fluorescein conjugated. FITC is one of the most widely used dyes for fluorescent applications, therefore most instruments come standard with a 488 nm laser and FITC filter set up. FITC is commonly conjugated to secondary antibodies and used in applications such as flow cytometry, immunocytochemistry, and immunohistochemistry. FITC is relatively dim, sensitive to photobleaching and it is susceptible to changes is pH. There are better performing alternatives to FITC, like Vio®Bright 515, Alexa Fluor™ 488, iFluor® 488, CF®488A and DY-488. FITC is a long-time generic dye with no sole manufacturer or trademark.
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FITC Excitation and Emission Spectra