MCM3 / DyLight 488 / MCM3/8972R

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-24079G (View supplier product page)
Size 100 μl
Price $599.00
Antigen MCM3
Clone MCM3/8972R
Host Rabbit
Isotype IgG κ
Conjugate DyLight 488
Target Species Human
Applications IHC-P
Description MCM3 Antibody (MCM3/8972R) [DyLight 488]
About MCM3 and DyLight 488
MCM3 The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2018]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra