L1CAM / Alexa Fluor 405 / rL1CAM/9163

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-24084AF405 (View supplier product page)
Size 100 μl
Price $599.00
Antigen L1CAM
Clone rL1CAM/9163
Host Mouse
Isotype IgG2b κ
Conjugate Alexa Fluor 405
Target Species Human
Applications IHC-P
Description L1CAM Antibody (rL1CAM/9163) [Alexa Fluor® 405]
About L1CAM and Alexa Fluor 405
L1CAM The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. [provided by RefSeq, May 2013]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 405 Excitation and Emission Spectra