IRF-4 / DyLight 755 / MUM1/8274R

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-20718IR (View supplier product page)
Size 100 μl
Price $639.00
Antigen IRF-4
Clone MUM1/8274R
Host Rabbit
Isotype IgG κ
Conjugate DyLight 755
Target Species Human
Applications IHC-P
Description IRF4 Antibody (MUM1/8274R) [DyLight 755]
About IRF-4 and DyLight 755
IRF-4 The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra