CD11a / Alexa Fluor 488 / DF1524

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-11533AF488 (View supplier product page)
Size 100 μl
Price $629.00
Antigen CD11a
Clone DF1524
Host Mouse
Isotype IgG2b κ
Conjugate Alexa Fluor 488
Target Species Human
Applications FC, ICC, IF
Description Integrin alpha L/CD11a Antibody (DF1524) [Alexa Fluor® 488]
About CD11a and Alexa Fluor 488
CD11a ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
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Alexa Fluor 488 Excitation and Emission Spectra