CD125 / DyLight 680 / 1036601

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB2531Y (View supplier product page)
Size 100 μl
Price $539.00
Antigen CD125
Clone 1036601
Host Mouse
Isotype IgG1
Conjugate DyLight 680
Target Species Human
Applications FC
Description IL-5R alpha/CD125 Antibody (1036601) [DyLight 680]
About CD125 and DyLight 680
CD125 The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. [provided by RefSeq, Jul 2011]
DyLight 680 DyLight™ 680 has an excitation peak at 692 nm and an emission peak at 712 nm, and is spectrally similar to Alexa Fluor™ 680 and Cy5.5. DyLight™ 680 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 680 Excitation and Emission Spectra