IL-12 R beta 2 / Alexa Fluor 750 / 305719

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB19592S (View supplier product page)
Size 100 μl
Price $509.00
Antigen IL-12 R beta 2
Clone 305719
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 750
Target Species Human, Mouse
Applications ELISA
Description IL-12 R beta 2 Antibody (305719) [Alexa Fluor® 750]
About IL-12 R beta 2 and Alexa Fluor 750
IL-12 R beta 2 The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene. [provided by RefSeq, Apr 2012]
Alexa Fluor 750 Alexa Fluor™ 750 (AF750, Alexa 750) has an excitation peak at 749 nm and an emission peak at 775 nm, and is spetrally similar to Cy®7 (GE Healthcare), APC-Fire™ 750 (BioLegend), CF®®750 (Biotium), DyLight™ 750 (ThermoFisher Scientific), iFluor® 750 (ATT Bioquest) and iFluor® 790 (ATT Bioquest). Alexa 750 is often used as a tandem fluorophore in flow cytometry or used on its own in fluorescence microscopy, in-vivo fluorescence microscopy or super-resolution microscopy applications.
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Alexa Fluor 750 Excitation and Emission Spectra