HDAC5 / Unconjugated /
HDAC5 / Unconjugated /
Product Details
Supplier | Novus Biologicals, a Bio-Techne brand | |
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Catalog #: | NBP3-24895 (View supplier product page) | |
Size | 100 μl | |
Price | $519.00 | |
Antigen | HDAC5 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | Unconjugated | |
Target Species | Human | |
Applications | IHC, IHC-P | |
Description | HDAC5 Antibody |
About HDAC5 and Purified
HDAC5 | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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Citations
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Purified Excitation and Emission Spectra
$519.00
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