CD357 / Alexa Fluor 532 / 108619

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB5241X (View supplier product page)
Size 500 μl
Price $749.00
Antigen CD357
Clone 108619
Host Rat
Isotype IgG2a
Conjugate Alexa Fluor 532
Target Species Mouse
Applications WB, FC, CyTOF
Description GITR/TNFRSF18 Antibody (108619) [Alexa Fluor® 532]
About CD357 and Alexa Fluor 532
CD357 This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
Alexa Fluor 532 Alexa Fluor™ 532 (AF532, Alexa 532) has an excitation peak at 532 nm and an emission peak at 554 nm, and is spectrally similar to Cy®3 (GE Healthcare), TRITC, iFluor® 514 (ATT Bioquest) and iFluor® 546 (ATT Bioquest). Many flow cytometers are equipped with 532nm lasers, so while Alexa 532 can be used for flow cytometry, PE is more commonly used due to its brightness and spectral characteristics. This dye is commonly used for fluorescence microscopy applications.
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Alexa Fluor 532 Excitation and Emission Spectra