GAD65 / Alexa Fluor 647 / GAD2/6488R

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-20859AF647 (View supplier product page)
Size 100 μl
Price $629.00
Antigen GAD65
Clone GAD2/6488R
Host Rabbit
Isotype IgG κ
Conjugate Alexa Fluor 647
Target Species Human
Applications ELISA
Description GAD2/GAD65 Antibody (GAD2/6488R) [Alexa Fluor® 647]
About GAD65 and Alexa Fluor 647
GAD65 This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
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Alexa Fluor 647 Excitation and Emission Spectra