CD105 / DyLight 550 / ENG/8961R

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-24336R (View supplier product page)
Size 100 μl
Price $599.00
Antigen CD105
Clone ENG/8961R
Host Rabbit
Isotype IgG1 κ
Conjugate DyLight 550
Target Species Human
Applications IHC-P
Description Endoglin/CD105 Antibody (ENG/8961R) [DyLight 550]
About CD105 and DyLight 550
CD105 This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]
DyLight 550 DyLight™ 550 has an excitation peak at 562 nm and an emission peak at 576 nm and is spectrally similar to Alexa Fluor™ 546, Alexa Fluor™ 555, Cy3 and TRITC. DyLight™ 550 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 550 Excitation and Emission Spectra