EGF Receptor / DyLight 488 / EGFR/8933R

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-24208G (View supplier product page)
Size 100 μl
Price $599.00
Antigen EGF Receptor
Clone EGFR/8933R
Host Rabbit
Isotype IgG κ
Conjugate DyLight 488
Target Species Human
Applications IHC-P
Description EGFR Antibody (EGFR/8933R) [DyLight 488]
About EGF Receptor and DyLight 488
EGF Receptor The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). [provided by RefSeq, Jul 2020]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra