CD86 / Brilliant Violet 711 / IT2.2
CD86 / Brilliant Violet 711 / IT2.2
Citations:
(5)
Product Details
| Supplier | BioLegend | |
|---|---|---|
| Catalog #: | 305440 (View supplier product page) | |
| Size | 100T | |
| Price | $429.00 | |
| Antigen | CD86 | |
| Clone | IT2.2 | |
| Host | Mouse | |
| Isotype | IgG2b κ | |
| Conjugate | Brilliant Violet 711 | |
| Target Species | Cynomolgus macaque, Human, Rhesus macaque | |
| Applications | FC | |
| Description | Brilliant Violet 711 anti-human CD86 |
About CD86 and Brilliant Violet 711
| CD86 | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011] | |
|---|---|---|
| Brilliant Violet 711 | Brilliant™ Violet 711 (BV711) is a red-emitting tandem fluorophore that can be excited by the 405 nm Violet laser and collected using a 710/50 bandpass filter. BV711 has an excitation peak at 405 nm and an emission peak at 711 nm. BV711 exhibits a medium level of brightness and is most often used in flow cytometry, specifically, it is an alternative to nanocrystals used for intracellular flow. This dye is part of the Brilliant™ Violet dye line of fluorescent polymers. Brilliant™ Violet 421 polymer is employed as the donor molecule in a series of tandem dyes with acceptor molecules emitting at various points across the visible light spectrum. The Brilliant™ Violet dyes are a superior alternative to QDot nanocrystals and similar to SuperNova dye from Beckman Coulter and StarBright dyes from Bio-Rad. |
Images
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Human peripheral blood monocytes were stained with CD86 (clone IT2.2) Brilliant Violet 711™ (filled histogram) or mouse IgG2b, κ Brilliant Violet 711™ (open histogram). |
Citations
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Reviews & Ratings
Brilliant Violet 711 Excitation and Emission Spectra
$429.00
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