CD324 / DyLight 405 / rCDH1/6769

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-23977V (View supplier product page)
Size 100 μl
Price $599.00
Antigen CD324
Clone rCDH1/6769
Host Mouse
Isotype IgG1 κ
Conjugate DyLight 405
Target Species Human
Applications IHC-P
Description E-Cadherin Antibody (rCDH1/6769) [DyLight 405]
About CD324 and DyLight 405
CD324 This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015]
DyLight 405 DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

DyLight 405 Excitation and Emission Spectra