CD112 / PerCP-Cy5.5 / TX31

Citations: (1)
Product Details
Supplier BioLegend
Catalog #: 337416 (View supplier product page)
Size 100T
Price $382.00
Antigen CD112
Clone TX31
Host Mouse
Isotype IgG1 κ
Conjugate PerCP-Cy5.5
Target Species Human
Applications FC
Description PerCP/Cyanine5.5 anti-human CD112 (Nectin-2)
About CD112 and PerCP-Cy5.5
CD112 This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
PerCP-Cy5.5 PerCP-Cyanine® 5.5 (PerCP-Cy5.5) is a red-emitting tandem fluorophore that was originally designed to make the PerCP fluorophore more stable and increase signal intensity. The donor molecule, PerCP can be excited by the 488-nm blue laser and and transfers energy to the acceptor molecule, Cy5.5, which emitts light that can be captured with a 695/40 nm bandpass filter. PerCP-Cy5.5 has an excitation peak at 482 nm and an emission peak at 695 nm. There are superior alternatives to PerCP and PerCP-Cy5.5 including RealBlue 705 (BD Biosciences), NovaFluor Blue 690 or PerCP-eFluor™ 710.
Images
  CD112 PerCP-Cy5.5 BioLegend antibody anti target:Human host:Mouse isotype:IgG1 κ clone:TX31

Human myeloid leukemia cell line KG1a was stained with human CD112 (clone TX31) PerCP/Cy5.5 (filled histogram) or mouse IgG1, κ PerCP/Cy5.5 isotype control (open histogram).
Citations
PMID 23326467
PMID 24130898
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PerCP-Cy5.5 Excitation and Emission Spectra