Cytokeratin 8 / DyLight 488 / C-43

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-11481G (View supplier product page)
Size 100 μl
Price $629.00
Antigen Cytokeratin 8
Clone C-43
Host Mouse
Isotype IgG1 κ
Conjugate DyLight 488
Target Species Bovine, Human, Porcine, Rabbit, Sheep
Applications WB, IHC, ICC, IF, IHC-P
Description Cytokeratin 8 Antibody (C-43) [DyLight 488]
About Cytokeratin 8 and DyLight 488
Cytokeratin 8 This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra