CSK / PerCP / 7C6

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-59500PCP (View supplier product page)
Size 100 μl
Price $499.00
Antigen CSK
Clone 7C6
Host Mouse
Isotype IgG2b κ
Conjugate PerCP
Target Species Human
Applications WB, ELISA, ICC, IF
Description CSK Antibody (7C6) [PerCP]
About CSK and PerCP
CSK The protein encoded by this gene is involved in multiple pathways, including the regulation of Src family kinases. It plays an important role in T-cell activation through its association with the protein encoded by the protein tyrosine phosphatase, non-receptor type 22 (PTPN22) gene. This protein also phosphorylates C-terminal tyrosine residues on multiple substrates, including the protein encoded by the SRC proto-oncogene, non-receptor tyrosine kinase gene. Phosphorylation suppresses the kinase activity of the Src family tyrosine kinases. An intronic polymorphism (rs34933034) in this gene has been found to affect B-cell activation and is associated with systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]
PerCP Peridinin-Chlorophyll-Protein (PerCP) is a red-emitting fluorescent protein isolated from algae that can be excited by the 488 nm blue laser and captured with a 670/30 nm bandpass filter. PerCP exhibits a large Stokes' Shift, with an excitation peak at 482 nm and an emission peak at 675 nm. PerCP is was historically used in flow cytometry, however it is highly susceptible to photobleaching and has poor stability. Alternatives like BB700, NovaFluor Blue 690 or PerCP-eFluor™ 710 are preferred. PerCP is a generic dye that has no sole manufacturer.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

PerCP Excitation and Emission Spectra