Coagulation Factor XI / Alexa Fluor 488 / 6

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-89239AF488 (View supplier product page)
Size 100 μl
Price $549.00
Antigen Coagulation Factor XI
Clone 6
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 488
Target Species Human
Applications ELISA
Description Coagulation Factor XI Antibody (006) [Alexa Fluor® 488]
About Coagulation Factor XI and Alexa Fluor 488
Coagulation Factor XI This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq, Jul 2008]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
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Alexa Fluor 488 Excitation and Emission Spectra