Chk1 / HRP /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-464H (View supplier product page)
Size 100 μl
Price $599.00
Antigen Chk1
Clone
Host Rabbit
Isotype IgG
Conjugate HRP
Target Species Human, Mouse
Applications IHC, IP, IHC-P
Description Chk1 Antibody [HRP]
About Chk1 and HRP
Chk1 The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011]
Citations
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Reviews & Ratings
HRP Excitation and Emission Spectra