CD68 / Janelia Fluor 646 / Y-2/131/47

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-50149JF646 (View supplier product page)
Size 100 μl
Price $449.00
Antigen CD68
Clone Y-2/131/47
Host Mouse
Isotype IgG1
Conjugate Janelia Fluor 646
Target Species Human
Applications WB
Description CD68/SR-D1 Antibody (Y-2/131/47) [Janelia Fluor® 646]
About CD68 and Janelia Fluor 646
CD68 This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
Janelia Fluor 646 Janelia Fluor® 646 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 646 has an excitation peak at 646 nm and an emission peak at 664 nm.
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Janelia Fluor 646 Excitation and Emission Spectra