IL-12 / Biotin / Polyclonal

Product Details
Supplier Thermo Fisher Scientific
Catalog #: PA184321 (View supplier product page)
Size 50 μg
Price $525.00
Antigen IL-12
Clone Polyclonal
Host Goat
Isotype IgG
Conjugate Biotin
Target Species Mouse
Applications ELISA, WB
Description IL-12 Polyclonal Antibody, Biotin conjugate. Interleukin 12 (IL12) can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine activated killer cells, and stimulate the production of IFN gamma by resting PBMC. IL12 induces IFN gamma, TNF alpha production in T and NK cells; costimulation of PBL proliferation; proliferation/differentiation of TH1 T lymphocytes. It is downregulated by IL10; homodimeric p40 antagonistic to functional p70 heterodimer. IL12R beta 1 binds p40 but when dimeric with IL12R beta 2 binds p35.ELISA 0.25-1 ug/ml, WB 0.1 - 0.2 µg/ml
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Biotin Excitation and Emission Spectra