CD46 / Alexa Fluor 405 / MCP/931

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-11539AF405 (View supplier product page)
Size 100 μl
Price $639.00
Antigen CD46
Clone MCP/931
Host Mouse
Isotype IgG2a κ
Conjugate Alexa Fluor 405
Target Species Human
Applications FC, ICC, IF
Description CD46 Antibody (MCP/931) [Alexa Fluor® 405]
About CD46 and Alexa Fluor 405
CD46 The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 405 Excitation and Emission Spectra