CD44 / Alexa Fluor 532 / HCAM/1097

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-11455AF532 (View supplier product page)
Size 100 μl
Price $639.00
Antigen CD44
Clone HCAM/1097
Host Mouse
Isotype IgG1 κ
Conjugate Alexa Fluor 532
Target Species Human, Mouse
Applications IHC, IHC-P
Description CD44 Antibody (HCAM/1097) [Alexa Fluor® 532]
About CD44 and Alexa Fluor 532
CD44 The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
Alexa Fluor 532 Alexa Fluor™ 532 (AF532, Alexa 532) has an excitation peak at 532 nm and an emission peak at 554 nm, and is spectrally similar to Cy®3 (GE Healthcare), TRITC, iFluor® 514 (ATT Bioquest) and iFluor® 546 (ATT Bioquest). Many flow cytometers are equipped with 532nm lasers, so while Alexa 532 can be used for flow cytometry, PE is more commonly used due to its brightness and spectral characteristics. This dye is commonly used for fluorescence microscopy applications.
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Alexa Fluor 532 Excitation and Emission Spectra