CD38 / DyLight 488 / rCD38/8045

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-21022G (View supplier product page)
Size 100 μl
Price $639.00
Antigen CD38
Clone rCD38/8045
Host Mouse
Isotype IgG1 κ
Conjugate DyLight 488
Target Species Human
Applications IHC-P
Description CD38 Antibody (rCD38/8045) [DyLight 488]
About CD38 and DyLight 488
CD38 The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra