CD86 / Alexa Fluor 594 / SPM600

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-11584AF594 (View supplier product page)
Size 100 μl
Price $629.00
Antigen CD86
Clone SPM600
Host Mouse
Isotype IgG1 κ
Conjugate Alexa Fluor 594
Target Species Human, Mouse, Rat
Applications IHC, ICC, IF, IHC-P
Description B7-2/CD86 Antibody (SPM600) [Alexa Fluor® 594]
About CD86 and Alexa Fluor 594
CD86 This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
Alexa Fluor 594 Alexa Fluor™ 594 (AF594, Alexa 594) has an excitation peak at 590 nm and an emission peak at 617 nm, and is spectrally similar to Texas Red (ThermoFisher Scientific), DyLight™ 594 (ThermoFisher Scientific), iFluor® 594 (ATT Bioquest) and iFluor® 610 (ATT Bioquest), CF®594 (Biotium), and ATTO 594 (ATTO-TEC). Alexa 594 is commonly used for flow cytometry,fluorescence microscopy and super-resolution microscopy. It is very bright, photostable, and pH insensitive.
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Alexa Fluor 594 Excitation and Emission Spectra