Axin-1 / Janelia Fluor 646 /
Axin-1 / Janelia Fluor 646 /
Product Details
| Supplier | Novus Biologicals, a Bio-Techne brand | |
|---|---|---|
| Catalog #: | NBP3-18242JF646 (View supplier product page) | |
| Size | 100 μl | |
| Price | $499.00 | |
| Antigen | Axin-1 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Janelia Fluor 646 | |
| Target Species | Mouse | |
| Applications | WB | |
| Description | Axin-1 Antibody [Janelia Fluor® 646] |
About Axin-1 and Janelia Fluor 646
| Axin-1 | This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] | |
|---|---|---|
| Janelia Fluor 646 | Janelia Fluor® 646 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 646 has an excitation peak at 646 nm and an emission peak at 664 nm. |
Citations
| Additional Sources |
|
|---|
Reviews & Ratings
Janelia Fluor 646 Excitation and Emission Spectra
$499.00
Supplier Page
Supplier Page
