alpha-Methylacyl-CoA Racemase / DyLight 405 / AMACR/8350R

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-20847V (View supplier product page)
Size 100 μl
Price $629.00
Antigen alpha-Methylacyl-CoA Racemase
Clone AMACR/8350R
Host Rabbit
Isotype IgG κ
Conjugate DyLight 405
Target Species Human
Applications IHC-P
Description alpha-Methylacyl-CoA Racemase/AMACR Antibody (AMACR/8350R) [DyLight 405]
About alpha-Methylacyl-CoA Racemase and DyLight 405
alpha-Methylacyl-CoA Racemase This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]
DyLight 405 DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 405 Excitation and Emission Spectra