Agrin / Alexa Fluor 488 / AGR 131

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB110-11069AF488 (View supplier product page)
Size 100 μl
Price $499.00
Antigen Agrin
Clone AGR 131
Host Mouse
Isotype IgG2a
Conjugate Alexa Fluor 488
Target Species Mouse, Rat
Applications WB, IHC, ICC, IF, IHC-P, Microarray
Description Agrin Antibody (AGR 131) [Alexa Fluor® 488]
About Agrin and Alexa Fluor 488
Agrin This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
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Alexa Fluor 488 Excitation and Emission Spectra