CD11b / Biotin / F6.2

Product Details
Supplier Thermo Fisher Scientific
Catalog #: MA112201 (View supplier product page)
Size 100 Tests
Price $255.00
Antigen CD11b
Clone F6.2
Host Mouse
Isotype IgG2a
Conjugate Biotin
Target Species Human
Applications FC
Description Monoclonal
About CD11b and Biotin
CD11b This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Citations
Additional
Sources
Reviews & Ratings
Biotin Excitation and Emission Spectra