ABCG5 / DyLight 650 / 1B5E10

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-80559C (View supplier product page)
Size 100 μl
Price $499.00
Antigen ABCG5
Clone 1B5E10
Host Mouse
Isotype IgG1
Conjugate DyLight 650
Target Species Human
Applications WB, FC, ELISA, IHC, IHC-P, CyTOF, N/A
Description ABCG5 Antibody (1B5E10) [DyLight 650]
About ABCG5 and DyLight 650
ABCG5 The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008]
DyLight 650 DyLight™ 650 is a red-emitting fluorophore that excited by the 640 nm laser and collected using a 670/30 nm bandpass filter. DyLight™ 650 has an excitation peak at 652 nm and an emission peak at 672 nm, and is spectrally similar to Alexa Fluor™ 647 and Cy5. DyLight™ 650 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 650 Excitation and Emission Spectra