ABCC11 / Janelia Fluor 549 / ABCC11/2438

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-24276JF549 (View supplier product page)
Size 100 μl
Price $599.00
Antigen ABCC11
Clone ABCC11/2438
Host Mouse
Isotype IgG2b κ
Conjugate Janelia Fluor 549
Target Species Human
Applications IHC-P
Description ABCC11 Antibody (ABCC11/2438) [Janelia Fluor® 549]
About ABCC11 and Janelia Fluor 549
ABCC11 The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]
Janelia Fluor 549 Janelia Fluor® 549 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 549 has an excitation peak at 549 nm and an emission peak at 571 nm.
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Janelia Fluor 549 Excitation and Emission Spectra