CD25 / StarBright Violet 515 / K231.3B2

Product Details
Supplier Bio-Rad
Catalog #: MCA1736SBV515 (View supplier product page)
Size 100 Tests/0.5ml
Price $539.00
Antigen CD25
Clone K231.3B2
Host Mouse
Isotype IgG1
Conjugate StarBright Violet 515
Target Species Porcine
Applications FC
Description MOUSE ANTI PIG CD25:StarBright Violet 515
About CD25 and StarBright Violet 515
CD25 The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. Patients with severe Coronavirus Disease 2019 (COVID-19), the disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have significantly elevated levels of IL2R in their plasma. Similarly, serum IL-2R levels are found to be elevated in patients with different types of carcinomas. Certain IL2RA and IL2RB gene polymorphisms have been associated with lung cancer risk. [provided by RefSeq, Jul 2020]
StarBright Violet 515 StarBright Violet 515 (SBV515) is a fluorescent polymer nanoparticle that has an excitation peak at 402 nm and an emission peak at 516 nm, spectrally comparable to BV510. The StarBright family fluorophores from Bio-Rad offers an alternative to the Horizon Brilliant™ polymer series from BD Biosciences including Brilliant™ UV and Brilliant™ Violet.
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StarBright Violet 515 Excitation and Emission Spectra