SUN2 / Unconjugated / 3.1E

Product Details
Supplier BioLegend
Catalog #: 620752 (View supplier product page)
Size 100 μg
Price $485.00
Antigen SUN2
Clone 3.1E
Host Mouse
Isotype IgG1 κ
Conjugate Unconjugated
Target Species Human, Mouse, Rat
Applications WB, IHC-P, ICC
Description Purified anti-Sun2
About SUN2 and Purified
SUN2 SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM, Nov 2010]
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Purified Excitation and Emission Spectra