CD11a / NovaFluor Yellow 700 / M17/4

Product Details
Supplier Thermo Fisher Scientific
Catalog #: M054T02Y06 (View supplier product page)
Size 25 μg
Price $185.00
Antigen CD11a
Clone M17/4
Host Rat
Isotype IgG2a κ
Conjugate NovaFluor Yellow 700
Target Species Mouse
Applications FC
Description CD11a (LFA-1alpha) Monoclonal Antibody (M17/4), NovaFluor™ Yellow 700, eBioscience™
About CD11a and NovaFluor Yellow 700
CD11a ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
NovaFluor Yellow 700 The NovaFluor family of fluorescent polymers from Thermo Fisher Scientific are a novel reagent for traditional and spectral flow cytometry. These fluorophores are comprised of a DNA backbone polymer integrated with fluorophore substituted nucleosides to create a potent donor molecule. Tandem fluophores with long Stokes' Shift enable brighter, spectrally discrete, tunable fluorescent polymers as an alternative to traditional simple organic structures, protein-based fluorophores as well as the Horizon Brilliant™ family of fluorescent polymers from BD. NovaFluor Yellow 700 is designed to be discreetly excited by the 561nm laser and has an excitation peak at 552 nm and an emission peak at 700 nm.
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NovaFluor Yellow 700 Excitation and Emission Spectra