Perilipin-2 / CF568 / rADFP/1493

Product Details
Supplier Biotium
Catalog #: BNC683185-500 (View supplier product page)
Size 500 μl
Price $551.00
Antigen Perilipin-2
Clone rADFP/1493
Host Mouse
Isotype IgG1 κ
Conjugate CF568
Target Species Human
Applications IHC, IHC-P
Description Perilipin-2, also known as Adipophilin, belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This 48 kDa protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
About Perilipin-2 and CF568
Perilipin-2 The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]
CF568 CF®568 from Biotium is a fluorophore with an excitation peak at 562 nm and an emission peak at 583 nm. It can be useful in both fluorescence microscopy and flow cytometry. It is spectrally similar to Alexa Fluor™ 568 and ATTO 565. However, in flow cytometry, a superior alternative is R-PE. In microscopy, CF®568 is validated in super-resolution imaging by STORM, STED, Structured Illumination (SIM) and TIRF.
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CF568 Excitation and Emission Spectra