PD-1 / CF594 / NAT105

Product Details
Supplier Biotium
Catalog #: BNC940896-500 (View supplier product page)
Size 500 μl
Price $551.00
Antigen PD-1
Clone NAT105
Host Mouse
Isotype IgG1 κ
Conjugate CF594
Target Species Human
Applications IHC, IHC FFPE
Description PDCD1 / PD1 / CD279 (Programmed Cell Death 1)(NAT105), CF594 conjugate, 0.1mg/mL
About PD-1 and CF594
PD-1 Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
CF594 CF®594 from Biotium is a fluorophore with an excitation peak at 593 nm and an emission peak at 614 nm. It can be useful in both fluorescence microscopy and flow cytometry. It is spectrally similar to Alexa Fluor™ 594, DyLight™ 594 and Texas Red. However, in flow cytometry, PE-CF®594 and PE-Dazzle 594 are superior alternatives. In microscopy, CF®594 has been validated in STED and 2-Photon microscopy.
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CF594 Excitation and Emission Spectra