PD-1 / CF488A / NAT105

Product Details
Supplier Biotium
Catalog #: BNC880896-500 (View supplier product page)
Size 500 μl
Price $551.00
Antigen PD-1
Clone NAT105
Host Mouse
Isotype IgG1 κ
Conjugate CF488A
Target Species Human
Applications IHC, IHC FFPE
Description PDCD1 / PD1 / CD279 (Programmed Cell Death 1)(NAT105), CF488A conjugate, 0.1mg/mL
About PD-1 and CF488A
PD-1 Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
CF488A CF®488A from Biotium is a fluorophore with an excitation peak at 490 nm and an emission peak at 515 nm. It is spectrally similar to Fluorescein, Alexa Fluor™ 488 and DyLight™ 488. It can be use in fluorescence microscopy and flow cytometry. In microscopy, CF®488A has been specifically validated for STORM, STED, Structured Illumination (SIM), 2-Photon microscopy and TIRF.
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CF488A Excitation and Emission Spectra