Pappalysin-1 / Biotin / PAPPA/2716

Product Details
Supplier Biotium
Catalog #: BNCB2716-500 (View supplier product page)
Size 500 μl
Price $551.00
Antigen Pappalysin-1
Clone PAPPA/2716
Host Mouse
Isotype IgG2b κ
Conjugate Biotin
Target Species Human
Applications IHC, IHC FFPE
Description PAPP-A / Pappalysin-1 (Marker of Atherosclerosis and Aneuploid Fetus)(PAPPA/2716), Biotin conjugate, 0.1mg/mL
About Pappalysin-1 and Biotin
Pappalysin-1 This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). Following IGFBP cleavage, insulin growth factors dissociate from IGFBPs and bind to IGF receptors, resulting in activation of the IGF pathway. The encoded protein plays a role in bone formation, inflammation, wound healing and female fertility. Enhanced expression of this protein is associated with diabetic nephropathy in human patients and this protein may promote tumor invasion and growth in various human cancers. [provided by RefSeq, Aug 2017]
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Biotin Excitation and Emission Spectra