GnRHR / CF594 / GNRHR/2982R

Product Details
Supplier Biotium
Catalog #: BNC942982-500 (View supplier product page)
Size 500 μl
Price $551.00
Antigen GnRHR
Clone GNRHR/2982R
Host Rabbit
Isotype IgG
Conjugate CF594
Target Species Human
Applications
Description GnRH-Receptor / LH-RH Receptor(GNRHR/2982R), CF594 conjugate, 0.1mg/mL
About GnRHR and CF594
GnRHR This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq, Jul 2008]
CF594 CF®594 from Biotium is a fluorophore with an excitation peak at 593 nm and an emission peak at 614 nm. It can be useful in both fluorescence microscopy and flow cytometry. It is spectrally similar to Alexa Fluor™ 594, DyLight™ 594 and Texas Red. However, in flow cytometry, PE-CF®594 and PE-Dazzle 594 are superior alternatives. In microscopy, CF®594 has been validated in STED and 2-Photon microscopy.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

CF594 Excitation and Emission Spectra