CD326 / CF514 / 323/A3

Product Details
Supplier Biotium
Catalog #: BNC140396-100 (View supplier product page)
Size 100 μl
Price $199.00
Antigen CD326
Clone 323/A3
Host Mouse
Isotype IgG1 κ
Conjugate CF514
Target Species Human
Applications FC, IHC, IHC-P
Description EGP40 is a 40-43 kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
About CD326 and CF514
CD326 This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]
CF514 CF®514 from Biotium is a fluorophore with an excitation peak at 516 nm and an emission peak at 548 nm. It is spectrally similar to Alexa Fluor™ 514.
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CF514 Excitation and Emission Spectra