Cytochrome P450 1A1/2 / Biotin / MC1

Product Details
Supplier Biotium
Catalog #: BNCB2907-500 (View supplier product page)
Size 500 μl
Price $551.00
Antigen Cytochrome P450 1A1/2
Clone MC1
Host Mouse
Isotype IgG1 κ
Conjugate Biotin
Target Species Human, Mouse, Primate, Rat
Applications
Description Cytochrome P450 oxidase (commonly abbreviated CYP) is a generic term for a large number of related, but distinct, oxidative enzymes important in vertebrate physiology. The cytochrome P450 mixed-function monooxygenase system is probably the most important element of Phase I metabolism in mammals. P450s are membrane-bound, either in the inner membrane of mitochondria or in the endoplasmic reticulum of cells where they metabolise thousands of endogenous and exogenous compounds. In the liver, these substrates include toxins, drugs, and other unneeded and potentially harmful molecules. Humans have 18 families of cytochrome P450 genes and 43 subfamilies; the CYP1 family is involved in drug metabolism and includes 3 subfamilies, 3 genes and 1 pseudogene. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Citations
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Reviews & Ratings
Biotin Excitation and Emission Spectra