CD3e / CF568 / UCHT1
CD3e / CF568 / UCHT1
Product Details
Supplier | Biotium | |
---|---|---|
Catalog #: | BNC682473-500 (View supplier product page) | |
Size | 500 μl | |
Price | $551.00 | |
Antigen | CD3e | |
Clone | UCHT1 | |
Host | Mouse | |
Isotype | IgG1 κ | |
Conjugate | CF568 | |
Target Species | Chimpanzee, Human | |
Applications | Functional, ELISA, FC, FC, IF, IP, WB | |
Description | Recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors. |
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CF568 Excitation and Emission Spectra
$551.00
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