FluoroFinder

	Supplier	Biotium
	Catalog #:	BNC472742-500 (View supplier product page)
	Size	500 μl
	Price	$551.00
	Antigen	CD274
	Clone	PDL1/2742
	Host	Mouse
	Isotype	IgG1 κ
	Conjugate	CF647
	Target Species	Human
	Applications
	Description	PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

	Additional Sources

$551.00
Supplier Page

CD274 / CF647 / PDL1/2742