CD207 / Biotin / LGRN/1821

Product Details
Supplier Biotium
Catalog #: BNCB1821-100 (View supplier product page)
Size 100 μl
Price $199.00
Antigen CD207
Clone LGRN/1821
Host Mouse
Isotype IgG2a κ
Conjugate Biotin
Target Species Human
Applications
Description Langerin / CD207 (Marker of Langerhans Cells)(LGRN/1821), Biotin conjugate, 0.1mg/mL
About CD207 and Biotin
CD207 The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. [provided by RefSeq, Aug 2010]
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Biotin Excitation and Emission Spectra