CD192 / RealYellow 586 / Y15-488.rMAb

Product Details
Supplier BD Biosciences
Catalog #: 568535 (View supplier product page)
Size 100 μg
Price $436.00
Antigen CD192
Clone Y15-488.rMAb
Host Rat
Isotype IgG1 κ
Conjugate RealYellow 586
Target Species Mouse
Applications FC
Description Ms CD192 (CCR2) RY586 Y15-488.RMAB 100ug
About CD192 and RealYellow 586
CD192 The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. [provided by RefSeq, Aug 2017]
RealYellow 586 BD Horizon RealYellow 586 (RY586) is a bright, yellow emitting dye used in flow cytometry. This fluorophore is excited optimally by the 561 laser and is similar in its emission properties to PE, but interestingly, RY586 shows minimal cross-laser excitation with the 488 laser and can be used in spectral flow cytometry panels concurrently with PE (as stated by supplier).
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RealYellow 586 Excitation and Emission Spectra