Ly-6C RealBlue 705 (AL-21, Rat) - Reactivity: Mouse
Product Details
| Description |
The AL-21 monoclonal antibody specifically binds to a non-polymorphic determinant of Ly-6C, a 14-17 kDa GPI-linked cell-surface antigen found on some monocyte/macrophage populations, granulocytes, endothelial cells, plasma cells, and thymocyte, NK-cell, and T-subsets. Mice with the Ly-6.2 alloantigen (eg, AKR, C57BL, C57BR, C57L, C58, DBA/2, PL, SJL, SWR, 129) have subsets of CD8+ and CD4+ Ly-6C+ T cells, while Ly-6.1 strains (eg, A, BALB/c, CBA, C3H/He, DBA/1, NZB) have only CD8+ Ly-6C+ T cells. Upregulation of Ly-6C expression on CD8+ T cells by interferons α and β and poly (I:C) has been described, and Ly-6C is a memory marker on CD8+ T cells. |
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| Conjugate | RealBlue 705 | |
| Clone | AL-21 | |
| Target Species | Mouse | |
| Applications | FC | |
| Supplier | BD Biosciences | |
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About RealBlue 705
RealBlue™ 705 from BD Biosciences is a novel fluorescent multimer that exhibits improvements upon PerCP-Cy5.5 and BB700 due to lower cross beam excitation efficiency with the 355nm UV, 405nm violet, 561nm yellow/green and 633/647nm red lasers, which results in less spectral spillover and resultant spreading error associated with the use of this fluorophore in a multicolor panel.
RealBlue™ 705 from BD Biosciences is a novel fluorescent multimer that exhibits improvements upon PerCP-Cy5.5 and BB700 due to lower cross beam excitation efficiency with the 355nm UV, 405nm violet, 561nm yellow/green and 633/647nm red lasers, which results in less spectral spillover and resultant spreading error associated with the use of this fluorophore in a multicolor panel.
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